Leading Resin Manufacturer Purolite Extends Strategic Partnership with Repligen for Five New High-Performance Ligands to Meet Evolving Bioprocessing Market Needs

November 03, 2022

Wales, UK – 1st November 2022 -- Purolite, an Ecolab company and leading manufacturer of synthetic and agarose-based resins used in the bioprocessing industry, has expanded, and extended its agreement until 2032 with life sciences company Repligen Corporation to supply five ligands.

Repligen is a leading player in bioprocessing and long-time market leader in Protein A, with two facilities that produce the majority of the global Protein A ligand demand to biopharmaceutical customers worldwide.

Purolite’s jetting technology is a patented manufacturing method that produces agarose resins used in the purification of vital therapeutics such as monoclonal antibodies (mAbs). Jetting technology provides Purolite with precise control over bead size and distribution, creating unrivalled lot-to-lot consistency, unique productivity benefits and improved quality for biopharmaceutical developers. Furthermore, the technology significantly reduces lead times and is a greener alternative to traditional manufacturing methods.

Building upon a strong foundation of protein A solutions first commercialized in 2015, this new 10-year agreement will enable Purolite to further expand into the affinity space to provide more solutions for purification of mAbs and mAb fragments that are currently unmet by the market.

One of the highlights of the partnership is the development and commercialization of Praesto Jetted A50 HipH, which combines Purolite’s base beads with Repligen’s ligand technology to offer a novel protein A affinity resin, capable of eluting at milder conditions when compared to conventional protein A resins currently available to the bioprocessing market.

Hayley Crowe, Senior Vice President and General Manager of Purolite, said: “We are delighted that Repligen has chosen to extend and further strengthen its agreement with Purolite to continue to commercialize their affinity ligands which are specifically designed to target antibodies and fragments combined with our innovative Praesto agarose jetting base bead technology.

“We work closely to develop true partnerships with our customers to allow us to foresee the challenges of today and tomorrow. This continued partnership with Repligen is an example of Purolite working to meet the needs of customers globally by combining some of the most innovative technologies available on the market.”

“In parallel to this agreement, our investment and expansion into facilities on two continents highlights Purolite’s commitment to security of supply, reducing lead times and supporting manufacture of cost-effective therapies.”

“We look forward to continuing a productive relationship with Repligen and adding this ligand technology to our suite of products.”

Purolite is a leading manufacturer of ion exchange, catalyst, adsorbent and specialty resins. It has offices in more than 30 countries, with its global headquarters located in King of Prussia, Pennsylvania. The company’s King of Prussia facility is currently gearing up for agarose resin production, which will position Purolite as the first resin supplier with dual-continent production capabilities, providing leading security of supply to biopharmaceutical customers and CMOs globally.

For more information on this announcement, please visit the Purolite team on stand 121B83 (zone API) at CPHI 2022, in Frankfurt, where a member of their senior team will be pleased to discuss this announcement with you.

For further information, images and interview opportunities with Purolite, please contact: Aranda Rahbarkouhi at ramarketing | aranda@ramarketingpr.com | +44 07807 009 347

For more information, please visit www.purolite.com

About Purolite.

Purolite, an Ecolab company, is a leading manufacturer of healthcare & life science products, ion exchange, catalyst, adsorbent and specialty resins for water and non-water applications. Headquartered in King of Prussia, Pennsylvania, with 40 sales offices in more than 30 countries, the company has ISO 9001-certified manufacturing facilities in the USA, United Kingdom, China and Romania. With a large technical sales team, five R&D centers and four manufacturing facilities, Purolite is built to provide high-end, customized solutions to address some of the most complex challenges. 


About Ecolab.

A trusted partner at nearly three million customer locations, Ecolab (ECL) is the global leader in water, hygiene and infection prevention solutions and services that help protect people, planet and business health. With annual sales of $13 billion and more than 47,000 associates, Ecolab delivers comprehensive science-based solutions, data-driven insights and world-class service to advance food safety, help maintain clean and safe environments, optimize water and energy use, and improve operational efficiencies and sustainability for customers in the food, healthcare, hospitality and industrial markets in more than 170 countries around the world. www.ecolab.com


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