Bioquell Qube equipment

Bioquell Qube

The Bioquell Qube is a configurable isolator integrated with Bioquell Hydrogen Peroxide Sterilant (EPA Reg. No. 72372-1-86703). From its unique design to rapid cycle times, the Bioquell Qube helps ensure your aseptic workspace needs are met for a safe and productive working environment.

Bioquell Qube is Ideal for:

  • Sterility Testing 
  • Gene and Cell Therapy 
  • Small Batch Production 
  • Compounding 
  • Cytotoxic Preparation

Why Choose The Bioquell Qube

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Decontamination cycles in as little as 20 minutes; setup from order to completed installation and validation in as few as 12 weeks 

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Up to three chambers (two gloves per chamber) and two material transfer areas to meet your workflow needs; positive and negative pressure capabilities

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Customized validated cycles providing ISO 5/EU Grade A environment; GMP compliance; unidirectional airflow in accordance with GMP Annex 1; 21-CFR Part 11 software available

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Four levels of environmental monitoring for your viable and nonviable particle needs; ability to incorporate the Merck Millipore Sigma Symbio Flex Sterility Pump; other distinctive options to keep you working efficiently

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Built-in Bioquell hydrogen peroxide vapor technology using Bioquell Hydrogen Peroxide Sterilant for repeatable decontamination results; easy-to-use touch-screen; no HVAC connection required 

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Decontamination of materials in the main chamber while you work in another; aseptic-hold retention for typically seven days depending on your protocols

Applicable Solutions

Cell and Gene Therapy

The risk and financial impact of microbial contamination is exceptionally high during the cell-production procedure, making aseptic conditions essential to the handling of cell samples. Performing as many steps as possible under isolation and following effective disinfection is the safest method. Our flexible bio-decontamination solutions help you to maintain a secure environment free of microbiological contaminants so you can develop and advance leading therapies and treatments.

Pharmaceutical Manufacturing and Compounding

Stringent manufacturing and compounding conditions call for leading bio-decontamination solutions. Whether operated by your staff members or one of our expert onsite technicians, our fixed and portable hydrogen peroxide vapor bio-decontamination systems kill organisms on surfaces in your pass-throughs, airlocks and other areas for total working efficacy.

Research and Laboratory

We understand biological safety is key to your research processes. That’s why Bioquell from Ecolab offers flexible bio-decontamination solutions for research facilities both large and small, allowing you to lead the way without a contaminant slowing you down. From your benchtop to your entire workspace, our mobile and built-in systems reduce your bioburden at every step of your workflow.

Biotechnology and Drug Development

The strict and continual application of aseptic processing, environmental controls and monitoring are key to the approval and success of your final drug or product as a leading solution. With Bioquell’s automated, validated bio-decontamination, you have confidence in your bioburden reduction of your workspace and enhancements for sterility testing.


Environmental Monitoring

Aseptic environmental conditions with four monitoring modes ranging from manual to fully integrated particle monitoring with both viable and nonviable particle-counting options.

Sterility Test Pump

Up to two integrated Merck Millipore Steritest Symbio Flex sterility test pumps for improving your sterility test process, simplifying operations and freeing up workspace.

Glove Sleeve System 

Patented glove sleeve system allows for all surface of the glove and sleeves to be decontaminated; includes small, light Safe Change Cuff Rings. Design provides reassurance that all areas of the Bioquell Qube are decontaminated.

Rapid Transfer Port

Aseptic transfer of materials into and out of isolators with no break of containment or effect on ambient characteristics – available in both 190mm and 270mm.

Contact us to learn how Bioquell Qube accessories can help optimize your workflow.

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Bioquell Qube

Our technical experts can install and validate the Bioquell Qube in as quickly as two weeks in most instances.

Because the Bioquell Qube is easy to maneuver and fast to assemble, you often do not need any construction or electrical alterations to install. It can fit through 800mm (32-inch) door frames to be built directly in the designated area. It requires only a standard electrical outlet to function and, for positive pressure users, does not require connection to HVAC.

Validation includes training, installation, operational and performance qualification (IQ, OQ and PQ), validated cycles based on custom-load configurations, and all appropriate documentation.

Isolator FAQs

Will this offer 21-CFR Part 11 compliance?
Yes, we are able to offer an optional data logger for this purpose.

What is the internal floor of the Bioquell Qube made from?
The floor of the Bioquell Qube is constructed from 316 stainless steel to ensure resistance to scratching on the working surface.

I have a small sterility-test need right now. What happens when my needs change?
The Bioquell Qube allows you to add and expand the system as your testing needs change and grow.

How can I bring tubing or cables into the Bioquell Qube?
We have an option for fitting a floor-mounted one-inch triclover port in each chamber. This allows you to bring in liquid lines or cables securely into the body of the Bioquell Qube.

What sets the Bioquell Qube apart from traditional stainless steel options?
The Bioquell Qube is constructed of tough and hard-wearing polypropylene. Because of its construction, the Bioquell Qube can be installed and validated within 12 weeks and, in most cases, with minimal invasiveness to your operation or workflow.

Can you set alarms for the temperature inside the Bioquell Qube?

If I want to change pressure from positive to negative, do I need to change the filters or take any additional action to ensure it is safe to use?
The Bioquell Qube can be switched between pressure regimes using the touchscreen; no additional changes are needed.

Are there different leak tests programmed for the Bioquell Qube?
Yes, there are leak tests programmed for both positive and negative pressure.

Contact Us

Contact Ecolab to learn how the Bioquell Qube can support your cell and gene therapy operation and put you at the forefront of compliance, product safety and operational excellence.

Contact Ecolab Life Sciences

Ecolab Life Sciences is a trusted partner for quality, safety and efficiency in biopharmaceutical manufacturing. Contact us to learn how we can help you achieve your goals and keep you on the cutting edge.

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